It’s a Nietzsche quote.
The essential thing ‘in heaven and earth’ is . . . that there should be long obedience in the same direction; there thereby results, and has always resulted in the long run, something which has made life worth living.
It’s the title of a Eugene Peterson book on “the Psalms of Ascents”.
And if Bono gets his way…
I suspect that Bono’s interest in that quote stems from his friendship with Peterson, rather than any affection for Nietzsche. But whatever the case… it’s interesting.