Brain Electrophysiologist Wants €1 Billion To Model Entire Brain

“Brain researchers are generating 60,000 papers per year,” said Markram as he explained the concept in Bern. “They’re all beautiful, fantastic studies — but all focused on their one little corner: this molecule, this brain region, this function, this map.” The HBP would integrate these discoveries, he said, and create models to explore how neural circuits are organized, and how they give rise to behaviour and cognition — among the deepest mysteries in neuroscience. Ultimately, said Markram, the HBP would even help researchers to grapple with disorders such as Alzheimer’s disease. “If we don’t have an integrated view, we won’t understand these diseases,” he declared.

As the response at the meeting made clear, however, there is deep unease about Markram’s vision. Many neuroscientists think it is ill-conceived, not least because Markram’s idiosyncratic approach to brain simulation strikes them as grotesquely cumbersome and over-detailed. They see the HBP as overhyped, thanks to breathless media reports about what it will accomplish. And they’re not at all sure that they can trust Markram to run a project that is truly open to other ideas.

Read the details of the history and proposed future of Markram’s project, and the skepticism he is receiving about its viability in Nature.

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About Daniel Fincke

Dr. Daniel Fincke  has his PhD in philosophy from Fordham University and spent 11 years teaching in college classrooms. He wrote his dissertation on Ethics and the philosophy of Friedrich Nietzsche. On Camels With Hammers, the careful philosophy blog he writes for a popular audience, Dan argues for atheism and develops a humanistic ethical theory he calls “Empowerment Ethics”. Dan also teaches affordable, non-matriculated, video-conferencing philosophy classes on ethics, Nietzsche, historical philosophy, and philosophy for atheists that anyone around the world can sign up for. (You can learn more about Dan’s online classes here.) Dan is an APPA  (American Philosophical Practitioners Association) certified philosophical counselor who offers philosophical advice services to help people work through the philosophical aspects of their practical problems or to work out their views on philosophical issues. (You can read examples of Dan’s advice here.) Through his blogging, his online teaching, and his philosophical advice services each, Dan specializes in helping people who have recently left a religious tradition work out their constructive answers to questions of ethics, metaphysics, the meaning of life, etc. as part of their process of radical worldview change.


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