The first cutting of flesh took place in the flood (Genesis 9:11).
The second was the cutting of flesh in circumcision (Genesis 17:14), particularly the cutting off of those who refuse to cut the flesh.
Circumcision is a sign of the division of the human race, its cutting into Jew and Gentile. Circumcision is a sign of a coming flood, the cutting off of flesh at the cross when the flesh is cut in the circumcision of Jesus so that He can rise in the Spirit.