The image and quote come from Oné R. Pagán’s blog BaldScientist. The quote really is a great one. There is no approach to reality that bypasses mystery. Whether one posits that the ultimate first cause is a divine mind that simply exists, or a law of physics that simply exists and which keeps bringing universes into existence, mystery is not eliminated. And the challenge to formulating a coherent worldview is finding the balance between eagerness to push back the boundaries of what we can explain, while also learning to live with the fact that some answers will simply not be found in our lifetime, if ever.
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