Angelina Jolie, the Cancer Gene and My Friend

Angelina Jolie, the Cancer Gene and My Friend June 6, 2013

Judge Twyla Gray sat opposite me twirling her fork in the salad on her plate. 

She had just told me that she was going to have a prophylactic double mastectomy. Twyla, who was a cancer survivor, had learned that she carried the brca gene. This gene predisposed her to breast cancer.

It had been decades since Twyla went through a lumpectomy, chemo and then radiation to treat a small cancer doctors found in one of her breasts. At the time she was diagnosed, Twyla put her considerable wits to researching her cancer and interviewing treatment specialists all around the country. She had a small child and she wanted to live.

I remember quite clearly her husband reading the summary of a pathologist’s report concerning that cancer to me. It was an aggressive form of the disease, and the pathologist’s advice was that she needed aggressive treatment. Afterwards, I talked to a doctor friend of mine who told me that based on her experience with patients, a cancer of that type would eventually come back, no matter what Twyla did.

More than 20 years later, Twyla seemed to have proven the experts wrong. Test after test, check-up after check-up, she was cancer free. Her child grew up to be a fine person. Her marriage thrived. Her career took off and she ended up a district judge.

Everything was looking good for Twyla.

Then she had genetic testing and learned she had the brca gene. She would always be vulnerable to this type of cancer, which is what led her to make the appointment for what she had dreaded for a long, long time: Mutilating surgery.

I asked her how she was a few weeks later and learned that she had backed out of the surgery. Then, a few months after that, the cancer recurred. She beat it back.


Another year passed, and it recurred.


There was no beating it back this time. She would die of this disease. The docs gave her three months, but she fought and won a small, though costly, reprieve. Twyla lived another year after she got the three month prognosis. Some of that time was good time. But she earned those good days by enduring horrible treatments.

I have wondered if it would have made any difference if she had gone ahead with that surgery. In truth, I do not know. But part of me doubts it. I think that the time bomb had been ticking away in the form of an occult cancer cell hiding in a corner of her body for all those years she was “cancer free.”

That’s the purgatory of cancer. No matter how many times a cancer survivor gets a clean scan, they know, and everyone who loves them knows, that it may not be entirely true. The cancer may be playing its little waiting game before it comes charging back.

Angelina Jolie’s Appearance is Critical to Her Career

I read week before last about Angelina Jolie’s decision to have a prophylactic double mastectomy. From what I read, it sounds as if Ms Jolie has the same gene my friend had. She has not had cancer, so maybe, just maybe, the surgery will save her.

All I know is that I am grateful to her for coming forward with the revelation that she has gone through this surgery. That can’t have been easy for a woman whose appearance and body are critiqued mercilessly every time she puts her foot outside her door.

Ms Jolie makes her living at least partly on the fantasies her audience has about her and her appearance. Prophylactic double mastectomies don’t quite fit with the sexy macho woman she plays in film. That kind of reality is part of our vulnerable human condition, not the cartoon character perfection of the characters she often plays.

It was a risk for her to share this. But it may encourage some other person (men can die of breast cancer, too, especially if they carry the brca gene) who gets the frightening news that they carry this gene the push they need to go under the knife for what can only be described as terrible surgery.

I want to add that the genetic testing to uncover this gene is expensive. Because of that, most people will not take the test. But if you have a history of cancer in your family, as Twyla did, especially if you have a history of breast cancer, it might be worth looking into.

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4 responses to “Angelina Jolie, the Cancer Gene and My Friend”

  1. I never thought much of Angelina Jolie – I don’t even find her beautiful – but I find her behaviour both upright and, in its own way, courageous. As you point out, she has made public a fact that does not much agree with the fantasy she projects and on which she makes her living. For the decision itself, of course, all we have to know is that she lost a much-loved mother to the illness; add that she has six children, and it becomes a no-brainer. She can, after all, afford the best in medical care. But to go public with it took a certain amount of nerve and dignity.

    I have no cancer in my family, thank God, but I lost my dearest friend and the most beautiful woman I ever knew to it. I hate it as if it were a living thing.

  2. I think Angelina has decided that being around for her children is more important then viewers knowing that her breasts are real. She could have kept it secret and viewers would be none the wiser. But she is a very altruistic person and knows that she can save many lives by going public.

  3. I feel the same, Fabio.

    “I have no cancer in my family, thank God, but I lost my dearest friend and the most beautiful woman I ever knew to it. I hate it as if it were a living thing.”

  4. Angelina fortunately has the money to do the brave thing(s) she did in having the surgeries to remove her breasts and I think she either has had or is planning to have her ovaries removed, due to the cancer risk in that area too. If she helps one woman to get checked for the nasty gene with her going public that will be great. I can hope that even women who don’t have the financial means but feel they are at risk will be able to be tested and if necessary, have the elective surgery.