In the video below there is a very helpful segment beginning at 39:45 (click here to start it playing at that point, or use the slider below). The segment begins with MacArthur explaining that he has never really been depressed. Some Christians are a bit like MacArthur. To be honest, that can make it hard for them to empathize with the Piper’s of this world who goes on to describe how he had a period of his life where he was significantly depressed that lasted several years. MacAthur’s incredulous “Years?!” demonstrates how very differently they are wired.